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Tuesday, May 28, 2013

Cottrell Scholar Awards: Astronomy, Biochemistry, Biophysics, Chemistry, Physics

Introduction

The Cottrell Scholar awards, instituted in 1994, are named in honor of Frederick Gardner Cottrell, scientist, inventor and philanthropist. Dr. Cottrell founded Research Corporation in 1912 and provided means for scientific research and experimentation at scholarly institutions. He not only contributed fundamentally and practically to scientific knowledge, but he dedicated his career to enlisting science in the service of society (see Biography of Frederick Gardner Cottrell).
The Cottrell Scholar Award (CSA) program owes its origins to the foundation's concern with the apparent separation of teaching and research in Ph.D. institutions. Rather than being communities of university-scholars, universities are often perceived as collections of specialists. We seek to reinforce the growing awareness that these two functions are complementary rather than wholly or partially exclusive. We believe this convergence is essential for increasing the fraction of students who are attracted and retained in science.

Goals and Desired Outcomes

The main goal of the CSA program is to promote and support the university scholar model. University scholars are faculty members who have both excellent research programs and excellent approaches to student learning at the undergraduate level.
Desired outcomes of the CSA program include:
  • A culture shift in Ph.D.- granting institutions toward valuing the university scholar
  • Increased attraction and retention of undergraduates in science
  • Increased undergraduates from Ph.D.-granting institutions pursuing graduate degrees
A key objective of the program is to build a community of outstanding scholar-educators who are dedicated to becoming leaders in both research and teaching and who collectively have the potential to change the way science is taught nationally. Scholars are required to attend at least two annual Cottrell Scholar conferences while the award is active. The annual conference seeks to promote community among Cottrell Scholars and is held in early July in Tucson, AZ.

Eligibility

Eligible applicants are tenure-track faculty members at U.S. institutions whose primary appointment is in a Bachelor's and Ph.D.-granting department of astronomy, biochemistry, biophysics, chemistry, or physics, but not in a school of medicine or engineering. For the 2013 proposal cycle, eligibility is limited to faculty members who started their first tenure-track position anytime in calendar year 2010.

American Sleep Medicine Foundation (ASMF)

Strategic Research Award

The American Sleep Medicine Foundation (ASMF) is pleased to announce the 2013 Strategic Research Award.  This request for proposals (RFP) is aimed at soliciting high quality grant proposals that would propose research aimed at improving quality of health care delivery in the field of sleep medicine.
Up to three grants will be funded up to $100,000 each for a period of one year.

Overview

The ASMF is interested in measuring value in sleep medicine. Value is a ratio of measures of quality, service, safety, and outcomes in the numerator divided by costs over time in the denominator. The following are areas that were identified as sleep research needs:
  1. Care under a board certified sleep medicine specialist:
    The responsive proposal should describe research that studies a) the value of the board certified sleep medicine specialist in diagnosing and managing sleep diseases, as compared with strategies that do not include sleep specialists, b) the comparative effectiveness of collaborative chronic care models for sleep disease across primary, specialty, or collaborative health care settings with particular emphasis on the role of the sleep medicine specialist in differing care models, or c) comparative economic evaluations (such as cost analysis, cost-benefit analysis, cost-effectiveness analysis, or cost-utility analyses) between care of sleep disease supervised by sleep medicine specialists vs. primary care physicians.
  2. Telemedicine:
    The responsive proposal should describe research that evaluates effectiveness of telemedicine, in part or in whole, as a means to manage sleep diseases. Special attention should be given to measures of cost analysis, cost-benefit analysis, cost-effectiveness analysis, or cost-utility analyses and of clinically relevant outcome measures.
  3. Actigraphy:
    The responsive proposal should describe research developing an understanding of the diagnostic or therapeutic value of actigraphy as it relates to the practice of sleep medicine. Potential questions to address might include a) work clarifying the relative and unique contributions of actigraphy compared with polysomnography, sleep logs, or other standard diagnostic tests in the diagnosis of sleep diseases and measurement of treatment effects, or measurement of treatment adherence, or b) work clarifying the use of actigraphy in patients with hypersomnia, especially as an adjunct to the Multiple Sleep Latency Test or other objective tests used in establishing sleepiness. The successful proposal should generate information that allows one to compare the value of actigraphy with other methods of establishing or monitoring sleep disease diagnoses and therapy.
Research in the strategic areas listed above, or combination thereof, is urgent considering the fast-changing field of sleep medicine and the need to reduce costs and yet improve the value of healthcare. Considering the importance of the topic and the limited funds available, applications that propose work that will aid development of subsequent competitive proposals for larger grants to other award giving agencies (i.e., collection of pilot data, initiating appropriate collaborations and planning for a future grant submission to for example, NIH, AHRQ or PCORI) will be considered highly responsive. Such planning proposals would need to include an appropriate timeline for submission of subsequent applications to other grant giving agencies.
This RFP falls under the broad category of Health Services Research and would require a competitive application to have significant input from health services researchers and/or biostatisticians in the conception and design of the proposal. Applicants are strongly encouraged to secure collaboration from researchers with prior experience in health care implementation science.

Eligibility


Members of the AASM in good standing are eligible to apply.

Application Deadline


Candidates must complete the application process before August 15, 2013

For questions about the Strategic Research Award or other ASMF inquiries, please contact Laura Bentley, ASMF Coordinator at 630-737-9700 or lbentley@aasmnet.org

Seeking Innovative Ideas to Improve Data Collection in the Global Dairy Sector for Human Health and Well-Being

CHALLENGE CLOSE DATE: July 11, 2013
Scientists Without Borders, in partnership with The Sackler Institute for Nutrition Science at the New York Academy of Sciences and the Bill & Melinda Gates Foundation seeks bold, innovative, feasible, and scalable ideas to leapfrog existing approaches and significantly improve the collection, reporting, aggregation, and sharing of data associated with dairy production and consumption all along the smallholder dairy production value chain in, but not limited to, Sub-Saharan Africa and South Asia.
We are seeking ideas that will appropriately and successfully combine and integrate technology-based approaches and innovations with social and cultural factors, rather than focusing on any one approach in isolation. Additionally, we seek ideas that provide a clear model of sustainability - meaning an identified and measurable pathway to scale and adoption of the idea proposed - and platform or program models that are open and shared, can piggyback or integrate with existing technology or program initiatives, and that can accommodate additional functionality as needs evolve. Finally, solvers must be cognizant when proposing a solution of the resource constraints and technology limitations operating at the household or smallholder farmer level in the relevant geographies.
Reward: Up to $7,500 for novel, feasible, and cost-effective ideas and approaches that significantly improve the collection, reporting, aggregation, and sharing of data associated with smallholder dairy production and consumption in the developing world. There may be opportunities for the winning solver to work with the partners to further develop the selected idea.
Solvers:  We are seeking student solvers at all academic levels (ranging from the middle school to postdoctoral level) in order to access nontraditional creative minds and passionate problem-solvers.  We encourage students to form teams or other models of collaboration to engage as many different perspectives as possible.


SBE Doctoral Dissertation Research Improvement Grants

grants 
Cultural Anthropology 
Division of Behavioral and Cognitive Sciences
Deborah Winslow (on Leave), Program Director
Jeffrey Mantz, Program Director
Christopher McCarty, Program Director
Cultural Anthropology Dissertation Target Dates: January 15 and August 15
Indirect Costs Notice: Please note an important change to the treatment of indirect costs that was incorporated into the SBE Doctoral Dissertation Research Improvement Grants (SBE DDRIG) program solicitation (NSF 11-547). NSF's long-standing policy regarding the reimbursement of administrative costs is full reimbursement of indirect costs, based on the awardee's current Federally negotiated indirect cost rate agreement. To ensure consistency with Foundation and Federal-wide policies, proposals submitted in response to this program solicitation are subject to the awardee's current Federally negotiated indirect cost rate.
Several points should be noted about submissions of proposals for Doctoral Dissertation Research Improvement Grants to the Cultural Anthropology Program. They are:
  • Target Dates: January 15 and August 15, or the first federal business day thereafter if the date falls on a weekend or a federal holiday . We anticipate that the panels will meet around April and November of each year, and PIs will be notified within a few months thereafter.
  • Project Duration: In general, grants are awarded for up to 24 months.
  • Project Budget: Maximum of $20,000 in direct costs (plus added indirect costs)Budget guidelines
  • Select SBE Doctoral Dissertation Research Improvement Grants under "Program Announcement / Solicitation Number Selection" on the Cover Page.
  • Proposal Title should begin with "Doctoral Dissertation Research:".
  • Project Description must not exceed 10 pages (not 15 as specified in the GPG).
  • While some programs require a statement of the student's current academic status and degree progress, currently the Cultural Anthropology program does not.
  • The Principal Investigator should be the student's dissertation advisor, and the student should be the Co-Principal Investigator. It is expected that the student (Co-PI) will author the proposal, which will then be submitted through the university by the dissertation advisor (PI).
  • All proposals must be submitted electronically via Fastlane or Grants.gov. Since font size may change when printed out, applicants are strongly advised to print out their proposal before formally submitting it through Fastlane to verify fonts and margins.
If you have additional questions, then please contact one of the Program Directors listed above.

Dissertation Panel Advice to Students 
The panel reviews 50-150 proposals each meeting, and usually ranks less than 20% in the "must fund" category. While the proposals span the breadth of diversity in cultural anthropology, the top-ranked proposals share some strengths which more proposals could display. On the most general level, the panel notes that projects that advance our theoretical understanding are more scientifically meritorious than descriptive projects which add a case study of some (albeit fascinating and topical) situation. Outstanding proposals specify how the knowledge to be created advances our theoretical understanding of the study situation, so that people interested in similar situations in different contexts will learn from the project's outcome. The key is to be explicit in showing how the general theory explains the local situation, and in showing how the new knowledge from the local situation will advance the theory.
Follow the proposal preparation guidelines in the Doctoral Dissertation Program Announcement, especially the instructions for spacing (single-spaced), length (10 pages for the project description), font size (12 point is best, no smaller than 15 characters/2.5 cm), biographical sketch (two page maximum), and proposal summary (one page max, 200 words minimum.) The summary must address in separate paragraphs the "intellectual merit" and the "broader impacts". (See the GPG). The project title should begin with the words: "Dissertation Research:" Proposals that violate these regulations in an attempt to squeeze in more information antagonize reviewers and may be returned without consideration.
Use a clear and concise writing style. Reviewers will include anthropologists from a variety of specialty areas in cultural anthropology. It is possible that no specialist from your particular area of research will be on the panel. Defining key terms and keeping your proposal free of jargon will ensure that all reviewers will be able to understand your proposal and evaluate it fairly.
One of the areas in which the proposal will be evaluated is "Research Competence of the Student." You can provide information to reviewers in the body of the proposal as well as in your biographical sketch. Be sure to include relevant language skills and proficiency, training or experience with the data collection or analysis techniques proposed, and any other information which can help reviewers evaluate how well prepared you are to conduct the research.
At the end of the proposal, include only references cited (in alphabetical order by author’s last name) rather than a complete or general bibliography for your problem area.
Examples of interview schedules, questionnaires or task protocols, etc. may be included up to two pages of in appendices, but do not attach any appendix unless you have received permission from the NSF program director. Proposals without explicit permission for appendices may be held up or returned without review. Remember that reviewers are not obligated to read appendices, so critically important information should be in the body of the proposal. Letters testifying to local institutional sponsorship need not be appended but definitely should be cited in the proposal.
The following are suggested page limits for the Project Description. These are not hard-and-fast rules, but indicate reviewers' interests:
  • Statement of the research problem, specific aims, expectations, propositions or hypotheses, 1 page
  • Review of the literature and significance, 2 pages
  • Preliminary studies by the student, if any
  • Some discussion of the Broader Impacts of the project
  • Research Plan, 5 pages, which should include the following: research design; research site or source of data (references and citations are as important in your methods as in your theory section); data analysis plans; research schedule
The research plan should begin with a statement of the research problem, phrased as a question that your research will answer. It should go on to give an overview of the research design, relating it to the theory. This should be followed by a brief description of the research site. Data collection and analysis methods follow. Key concepts such as “class”, “identity”, “resilience”, etc. should be unpacked and operationalized so that reviewers know exactly what you are talking about. Theories, setting and methods should be tightly linked: Readers should learn what the researcher is going to do and how the specific activities to be engaged in relate to both theory and setting. Note that a mere listing of a method is not enough to tell a reader what the researcher plans and why. The term "participant observation", for example, is extraordinarily general and should be unpacked into its specific components, each related to the information outcome that is then related to the research design and theory.
Site, case, and informant selection form part of your sampling strategy, and should be explicitly justified by discussing how your new data will generalize to a relevant population or theory. "Snowball sampling," which has various limitations, is not appropriate for some projects and if proposed should be explicitly justified with respect to alternatives. Each method, whether it generates qualitative or quantitative data, should be justified in terms of the research aims. The key issue is to impress reviewers that the new knowledge from your project will be relevant to significant populations and theories.
Proposals also should include an analysis plan, although readers recognize that plans change in the process of fieldwork. Describe how you will use your data to answer your research questions and test your hypotheses. Describe the specific steps you will take to find themes, identify patterns, make comparisons, etc. A mere listing of software programs will not demonstrate to reviewers that you have seriously considered the research process in designing your proposal. It should be possible for a reviewer to look back to your specific aims and understand why each kind of data is being collected, and why a particular analytic technique is planned.
Reviewers are well aware that there are no perfect strategies for conducting research, but will be looking for evidence that you understand the strengths and weaknesses of the approach selected. In a competitive review process where only a subset of excellent proposals can be funded, reviewers need to be told how the new knowledge to be gained from your particular study will yield generalizations that advance our theoretical understanding of the problem.

Saturday, May 25, 2013

Museums, Libraries, Nonprofits Encouraged to Launch Programs as Part of 5th Digital Media and Learning Competition to Improve the Online Experience for Young People


MacArthur is exploring how digital media are changing the way young people learn, play, socialize, and participate in civic life. The goal is to make education more powerful for all students by creating more opportunities for more youth to engage in learning that is relevant to their lives and prepares them for success in school, the workplace, and their community

About

An opportunity and a challenge

The web is an open ended laboratory for connected learning and creating. It has made possible anywhere-anytime learning for all generations, and especially for youth, in ways previously unimaginable. It promotes interest driven learning with and from peers.
These dramatic developments in connected learning opportunities raise the challenge of digital citizenship:
    • to use the web and its resources well and safely;
    • to interact collaboratively with peers and across generations in productive ways;
    • to put web resources and networks to good civic purpose;
    • to advocate for effective and equitable web solutions to social problems; and
    • to develop web-based skills for productive purposes.

Project:Connect and the Connected Learning movement

The Connected Learning movement is meeting these challenges by helping make it easier for youth to learn, connect, make, contribute, and share online. And it calls on and encourages youth to become creators and stewards of an open, inviting, and safe web.
The Digital Media and Learning Competition, administered by HASTAC and supported by the MacArthur Foundation, and in collaboration with the Born This Way Foundation and Mozilla, is calling for proposals that offer youth a chance to “Project:Connect” this summer. The Project:Connect-Summer Youth Programming Competition for U.S. based organizations that support learning, youth development and civic engagement calls for Summer event and programming proposals to excite and enable youth to engage the web in civil, collaborative, productive, safe, and confidence-building ways.
A related Project:Connect – Open International Competition will be announced on May 28, 2013. Details about the competition will be posted on dmlcompetition.net on May 28.

Friday, May 24, 2013

NIAID Paylines As of May 20, 2013


NIAID Paylines for FY 2013

These paylines apply to applications reviewed for the September 2012, February 2013, and June 2013 Council meetings.
Grant TypesPaylineStatusDescription
R01 (non-new PIs)8 percentileFiscal YearResearch Projects for established investigators
R01 (new PIs)12 percentileFiscal YearResearch Projects for new and early-stage investigators
F3130 overall impact scoreInterimNRSA Individual Predoctoral Fellowships to Promote Diversity in Health-Related Research
F3225 overall impact scoreInterimNRSA Postdoctoral Fellowships
K (except K99)20 overall impact scoreInterimCareer Development Awards
R0320 overall impact scoreInterimSmall Grants
R1520 overall impact scoreInterimAcademic Research Enhancement Awards (AREA)
R2120 overall impact scoreInterimExploratory/Developmental Grants
R41, R4226 overall impact scoreInterimSTTR Phase I and II—Small Business Technology Transfer
R43, R4422 overall impact scoreInterimSBIR Phase I and II—Small Business Innovation Research
T3213 overall impact scoreInterimInstitutional NRSA Training Awards

Bridge & Springboard Grants


Bridge Grant

Alex’s Lemonade Stand Foundation introduces a new funding opportunity for researchers whose projects are in jeopardy due to the decreased funding available from the National Institutes of Health (NIH). ALSF’s Bridge Grants are intended to keep scientist’s projects on track while they reapply for NIH funding to ensure novel childhood cancer research projects are not compromised. ALSF’s Bridge Grant awards will provide $100,000 for 12 months to be used for supplies, personnel or the Principal Investigator’s salary.
Eligibility Requirements:
  • Project must have been previously funded by an NIH R01, R03, R21 or P01 Award. (R01 Supplements are not eligible for Bridge Grants.)
  • Researchers must have applied to the NIH for an R01 or P01 renewal for an ongoing project or to continue the project via new R01 or P01 within the last 6 months.
  • The application must have been scored ≤25th percentile, but outside of the agency’s fundable range.
  • Applicants must be reapplying for an R01 or P01 Award from the NIH within the next two NIH Grant cycles.
  • Projects must be aligned with ALSF’s mission, thus focused on better diagnosing or curing childhood cancers.
  • Funds may be used for supplies, personnel or PI’s salary and may not exceed $100,000. ALSF does not pay indirect costs.  
   
Application Process:
  • To expedite the application progress, ALSF’s Scientific Advisory Board will review the previously reviewed NIH application along with any changes that have been made in response to feedback from NIH reviews.
  • A cover letter, summary statement, response to NIH critique and budget will be required by all applicants.
  • All applications must be submitted via ALSF’s online application.
     

Springboard Grant

ALSF’s offers the Springboard Grant in response to cut-backs in National Institutes of Health (NIH) funding of new R01 and P01 applications. The Springboard Grant is designed to jump-start new projects with high impact potential for childhood cancer research while other funding is sought. Awards will provide $100,000 for 12 months to be used for supplies, personnel or the Principal Investigator’s salary.
Eligibility Requirements:
  • Researchers must have applied to the NIH for an R01 or P01 award within the last 6 months. (R01 Supplements are not eligible for Springboard Grants)
  • Applications must have scored ≤20%, but outside of the agency’s fundable range.
  • Applicants must be reapplying for an R01 or P01 award from the NIH within the next two NIH Grant cycles.
  • Projects must be aligned with ALSF’s mission thus focused on better diagnosing or curing childhood cancers.
  • Funds may be used for supplies, personnel or PI’s salary and may not exceed $100,000. ALSF does not pay indirect costs.  
Application Process:
  • To expedite the application progress, ALSF’s Scientific Advisory Board will review the previously reviewed NIH application along with any changes that have been made in response to feedback from NIH reviews.
  • A cover letter, summary statement, response to NIH critique and budget will be required by all applicants.
  • All applications must be submitted via ALSF’s online application.
     

Helen Hay Whitney Foundation supports early postdoctoral research training in all basic biomedical sciences.


The Helen Hay Whitney Foundation supports early postdoctoral research training in all basic biomedical sciences.
To attain its ultimate goal of increasing the number of imaginative, well-trained and dedicated medical scientists, the Foundation grants financial support of sufficient duration to help further the careers of young men and women engaged in biological or medical research. 
Eligibility
Candidates who hold, or are in the final stages of obtaining a Ph.D., M.D., or equivalent degree and are seeking beginning postdoctoral training in basic biomedical research are eligible to apply for a fellowship. The Foundation accepts applications from candidates who have no more than one year of postdoctoral research experience at the time of the deadline for submitting the application (July 1, 2013), and who have received a PhD (or D.Phil. or equivalent) degree no more than two years before the deadline, or an M.D. degree no more than three years before the deadline.
Fellowships may be awarded to US citizens planning to work in laboratories either in the US, Canada, or abroad and also to foreign citizens for research in laboratories in the US only. We expect that most applicants will reside in North America at the time of application. Foreign Students will need to obtain appropriate visa documentation, as required by US Immigration.
Applications from established scientists or advanced fellows will not be considered. The fellowships are for early postdoctoral training only. Clinical house-staff training does not count as "postdoctoral laboratory training.”
The Foundation will not ordinarily consider applicants who plan tenure of the fellowship in the laboratory in which they have already received extensive predoctoral or postdoctoral training. The aim of the fellowship is to broaden postdoctoral training and experience, and a significant change of venue is advisable. Since the number of available fellowships is limited, the Foundation does not make more than one award in any one year for training with a given supervisor, and in addition, will not support more than two fellows per laboratory at one time.
The Foundation expects that fellowship training will be obtained in an academic setting. The selection of a commercial or industrial laboratory for the training experience is not acceptable.

Applications
Applications are to be filled out and submitted online at www.hhwf.orgApplications must be received by The Helen Hay Whitney Foundation no later than 5:00pm EST, July 1, 2013. Late applications will not be considered. 

Partnership for Clean Competition (PCC)


RESEARCH at PCC
PCC has been supporting high-quality, high-impact, novel research since 2009, and continues to budget approximately US$2.0M annually to support scientific studies that are likely to generate methods or products that will contribute to and improve the anti-doping landscape.
The SCIENTIFIC RESEARCH PROGRAM represents PCC's primary core business activity, promoting original work that focuses on improving existing analytical methods for detecting particular drugs, developing analytical methods to test for substances not currently detectable, and discovering cost effective approaches for testing widely abused substances across all levels of sport.  The SCIENTIFIC RESEARCH PROGRAM is open to scientists and researchers worldwide and runs three times per year, with each round of proposals reviewed by a panel of established and highly respected experts.  Individual grant awards have ranged from US$60,000 to US$400,000+ with a turnaround time on awards averaging less than four months.
The following areas of investigation are related directly to the mission of the Corporation and reflect (but are not listed in order of and are exemplary not all inclusive) its potential research priority interests:
  • Developing methods of cost effective testing to detect and deter the use of banned and illegal substances at that may be utilized by colleges, high schools and youth sports associations, among others;
  • Developing testing protocols to detect designer substances used for doping purposes;
  • Research into a widely-available, cost-effective test for detecting Human Growth Hormone (HGH)
  • Developing an athlete passport system which utilizes longitudinal data
  • Exploring the uses of banned substances and the societal causes of the uses of such substances.
  • Improving existing analytical methods to detect particular drugs, e.g.,: GH, IGF-1, EPO, hCG , discrimination of exogenous and endogenous steroids , screening methods for common steroids, stimulants.
  • Developing analytical methods to detect performance enhancing drugs not currently detectable, e.g.,: Selective Androgen Receptor Modulators , identifying designer steroids, autologous blood transfusions, other forms of enhanced oxygen transport and use.
  • Discovering cost effective approaches for testing widely abused substance
  • Longitudinal studies to document urinary excretion patterns, metabolism and dose-concentration
  • Critical Reviews of the literature from which to develop Position Papers to support interpretation of laboratory data
  • Alternative specimens, (e.g., hair, sweat, saliva, interstitial fluid) for testingBetter understanding of how banned substances are used and the implications for the long-term health consequences of athletes
 APPLYING for a PCC GRANT 

                PCC runs a two-step grant application process, three times per year:

                                       Step I: PRE-application (open, see deadlines below)
                                       Step II:  FULL application (by invitation only) 

PCC reviews PRE-applications on a rolling basis. Applicants whose pre-applications align with PCC research objectives and show considerable potential are then invited to submit full grant applications.    

  • R1 PRE-applications due March 1            R1 FULL applications due April 1
  • R2 PRE-applications due July 1              R2 FULL applications due August 1
  • R3 PRE-applications due November 1    R3 FULL applications due December 1
  

Damon Runyon-Rachleff Innovation Award Prevention, Diagnosis or Treatment of Cancer


2013 Important Dates

> July 1, 2013 Application Deadline
> November 2013 Finalist Interviews
December 2013 Notification of Awardees
January 1, 2014 Funding Begins

Program Description

The Damon Runyon-Rachleff Innovation Award is designed to provide support for the next generation of exceptionally creative thinkers with “high-risk/high-reward” ideas that have the potential to significantly impact our understanding of and/or approaches to the prevention, diagnosis or treatment of cancer.
The Innovation Award is specifically designed to provide funding to extraordinary early career researchers who have an innovative new idea but lack sufficient preliminary data to obtain traditional funding. It is not designed to fund incremental advances. The research supported by the award must be novel, exceptionally creative and, if successful, have the strong potential for high impact in the cancer field.
Awards are made to institutions for support of the Damon Runyon-Rachleff Innovation Investigators. All awards are approved by the Board of Directors of the Damon Runyon Cancer Research Foundation acting upon the recommendation of the Innovation Award Committee.

Applications will be evaluated based on the following:

  • The applicant’s capacity to conduct bold, exceptionally creative research.
  • The novelty and creativity of the proposed research.  Incremental research will not be funded.
  • The potential of the proposed research to lead to advances that will significantly impact the prevention, diagnosis, treatment or basic understanding of cancer.
  • The applicant’s lack of resources to pursue the proposed research.

Program Sponsors

The Damon Runyon-Rachleff Innovation Award is funded by the generous support of Andrew and Debra Rachleff.

Eligibility

  • Institutional nominations are not required and there is no limit to the number of applications that can be received from a particular institution.
  • Applicants (including non-U.S. citizens) must be conducting independent research at a U.S. research institution.
  • Basic and translational/clinical projects will be considered.  Applications will be accepted from all scientific disciplines provided that the proposed research meets the selection criteria.
  • Applicants with a background in multiple disciplines are especially encouraged to apply.
  • Joint submission from collaborators working in different disciplines will be considered. (The collaborators will share the $450,000 award.) Each collaborator must meet the eligibility criteria.
  • Applicants must belong to one of the following categories:
    • Tenure-track Assistant Professors within the first three years of obtaining their initial Assistant Professor position. (Cut-off date: July 1, 2010.)
    • Clinical Instructors and Senior Clinical Fellows (in the final year of their sub-specialty training) holding an MD who are pursuing a period of independent research before taking a tenure-track faculty position.  Such individuals must have an exceptional record of research accomplishment, dedicated laboratory space and the support of their institution.
    • Distinguished Fellows with an exceptional record of research accomplishment identified by their institution to pursue an independent research program and who have dedicated laboratory space.  These candidates are markedly distinct from traditional postdoctoral fellows.  Examples: Whitehead Fellows, UCSF Fellows, Cold Spring Harbor Fellows.
      [Research Assistant Professors, Research Associate Professors, Research Scientists and Postdoctoral Fellows are not eligible.  If you are unsure about your eligibility for this award program, please contact the Foundation's Award Programs at 212.455.0520.]
  • Applicants are expected to commit a minimum of 80% of their time to conducting research.
  • Applicants may apply no more than two times.
  • Applicants must demonstrate that they have access to the resources and infrastructure necessary to conduct the proposed research.
  • The department must guarantee the Investigator is conducting the proposed research independently.

Funding

  • The award will be for a period of three years. Each award will provide a total of $450,000 in direct research costs.  The Award cannot be used for indirect costs or institutional overhead.
  • Awards will be paid in increments of $150,000 per year for three years.  However, the Innovation Award Committee will consider an accelerated payment schedule if an award recipient can demonstrate compelling need.
  • The Innovation Award funds are intended to be flexible and can be used for a variety of scientific needs including the Investigator’s salary, salaries for professional and technical personnel, special equipment, supplies and other miscellaneous items required to conduct the proposed research.
  • The submitted budgets should be realistic estimates of the funds required for the proposed research and be itemized by category according to the instructions on the budget form.
  • No part of this award may be used for indirect costs or institutional overhead.

Concurrent Funding

Since the goal of the Innovation Award is to fund high risk/high reward research that lacks sufficient preliminary data to secure traditional funding, the applicant should not have funding for this proposed project.
During the course of the award, award recipients are encouraged to seek additional funding to expand and further develop their projects.

Thursday, May 23, 2013

Outstanding Mentors are Eligible for Presidential Awards for Excellence in Science, Mathematics and Engineering Mentoring (PAESMEM)


Notice Number: NOT-OD-13-069
Key Dates
Release Date: May 20, 2013
Issued by
National Institutes of Health (NIH)
Purpose
The White House established the Presidential Awards for Excellence in Science, Mathematics and Engineering Mentoring (PAESMEM) program in 1996. The program is administered by the National Science Foundation (NSF) on behalf of the White House and is intended to identify outstanding individual and institutional mentoring efforts in all scientific fields including those supported by the NIH.  The PAESMEM is the highest national STEM mentoring award.

Individuals nominated for awards must be US Citizens or permanent residents.   An organizational nominee must be affiliated with a U.S. corporation, educational institution or agency, military or government agency, non-profit organization, or foundation.    Individual and organizational nominees must have demonstrated outstanding and sustained mentoring of underrepresented students, trainees, and/or early career scientists and engineers for at least 5 years.  Individuals and organizations in all public and private sectors are eligible including industry, academia, primary and secondary education, military and government, non-profit organizations, and foundations. Details about eligibility, the nomination process, review, and the nature of the award are available at www.nsf.gov/PAESMEM where you can find a recorded webinar on preparing and submitting nomination materials.

Candidates can be nominated by a colleague, administrator, or a student.  Self-nominations also are accepted.   Nomination packages are reviewed in a process administered by the NSF.  Selection of award recipients is coordinated with the Office of Science and Technology Policy (OSTP).  Awardees are invited to Washington DC for various recognition and award events.   Up to 16 new awards can be made in each year. The awards are bestowed for past work in the amount of $10,000. Nomination packages are due by June 5, 2013.     

High quality mentoring is important to the success of NIH programs as reinforced by the recent study of the Workgroup on Biomedical Research established under the aegis of the NIH Advisory Committee to the Director.  The report from the Workgroup can be found at http://acd.od.nih.gov/dbr.htm.   Accordingly, participation in the PAESMEM program is appropriate for NIH affiliated researchers and institutions.  PAESMEM operates harmoniously with several NIH programs and activities that foster mentoring.  Programs include NIH Ruth L. Kirschstein Research Training Grants and Institutional Career Development Awards among others.  Information on such activities can be found at http://grants.nih.gov/training/nrsa.htm and athttp://grants.nih.gov/training/careerdevelopmentawards.htm

Participants in NIH research with a strong history of mentoring are encouraged to apply for this special Presidential Award.
Inquiries
Information is available from the PAESMEM Team at PAESMEM@nsf.gov or by phone at 703-292-8640.  

Notice of Intent to Publish a Funding Opportunity Announcement for NIDA Program Project Grant Applications (P01)


Notice Number: NOT-DA-13-028
Key Dates
Release Date: May 22, 2013
Estimated Publication Date of Announcement:  July 2013 
First Estimated Application Due Date:  September 2013 
Earliest Estimated Award Date:  July 2014
Earliest Estimated Start Date:  July 2014
Issued by
National Institute on Drug Abuse (NIDA)

Purpose
The National Institute on Drug Abuse intends to reissue PAR-10-244 "NIDA Program Project Grant Applications (P01)".  The FOA is expected to be published in July 2013 with an application due date in September 2013.

This Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. 

This FOA will utilize the P01 activity code and must be submitted electronically.  NIH’s new Application Submission System & Interface for Submission Tracking (ASSIST) is available for the electronic preparation and submission of multi-project applications through Grants.gov to NIH. ASSIST replaces the Grants.gov downloadable forms currently used and provides many features to enable electronic multi-project application submission and improve data quality, including: pre-population of organization and PD/PI data, pre-submission validation of many agency business rules and the generation of data summaries in the application image used for review.
Inquiries
Please direct all inquiries to:

Mark Swieter, Ph.D.
Office of Extramural Affairs
National Institute on Drug Abuse (NIDA)
Telephone: 301-435-1389
Email: mswieter@mail.nih.gov

International Rett Syndrome Invites Letters of Intent for Rett Syndrome Research


Basic Program

IRSF announces the availability of Regular Research grants for international biomedical research to promote the understanding of MeCP2 in the pathogenesis of the neurobehavioral phenotype of Rett syndrome (RTT). We seek to gain a better understanding of the underlying pathology of the disorder leading to an amelioration of the symptoms and a cure for RTT. IRSF seeks to encourage research that encompasses innovative therapeutic approaches and state of the art diagnostic techniques. 

IRSF encourages applications within the following emphasis areas:
  • Understanding the role of MeCP2 during normal brain development
  • Characterizing the role of MeCP2, including MeCP2 target genes, in normal structure and function of the developing and adult nervous system
  • Determination of the relationship between patterns of expression of MeCP2, FoxG1, CDKL5, and related proteins in the nervous system and the neurologic and behavioral phenotypes of patients with RTT and/or related animal models
  • The investigation of neuronal abnormalities that result from MeCP2 dysfunction
  • The role of microglial and macroglial cells in development as it relates to RTT
  • Understanding mechanisms and systems leading to aberrant behavior in RTT
  • The development of assistive technologies to improve the quality of life of individuals affected by RTT
  • Support for other advances in therapy such as physical therapy, communication and education
The two year Regular Research Grants are designed to assist investigators establish hypotheses relevant to Rett syndrome research and obtain future funding from other agencies. The maximum funding level for research grants is $100,000 over two years. 

Frequency:Awards will be made in one cycle in 2013
Timeline:Letters of Intent due: July 1, 2013
Invitation of full applications by: July 19, 2013
Applications due: August 19, 2013

Peer Reviewed Cancer Research Program Career Development Award


SUBMISSION AND REVIEW DATES AND TIMES
 Pre-Application Submission Deadline: 5:00 p.m. Eastern time (ET), July 16, 2013
 Invitation to Submit an Application: September 2013
 Application Submission Deadline: 11:59 p.m. ET, October 22, 2013
 Peer Review: December 2013
 Programmatic Review: February 2014


Program Description
Applications to the Fiscal Year 2013 (FY13) Peer Reviewed Cancer Research Program (PRCRP)
are being solicited for the Assistant Secretary of Defense for Health Affairs, Defense Health
Program (DHP), by the U.S. Army Medical Research Acquisitions Activity (USAMRAA). The
PRCRP was initiated in 2009 to provide support for cancer research of exceptional scientific
merit not addressed by the breast cancer, prostate cancer, lung cancer, and ovarian cancer
research programs executed and managed by the Office of the Congressionally Directed Medical
Research Programs (CDMRP). Appropriations for the PRCRP from FY09 through FY12 totaled
$59.8 million (M). The FY13 appropriation is $15M.
The goal of the PRCRP is to improve quality of life by decreasing the impact of cancer on
service members, their families, and the American public. As such, the PRCRP will foster the
next generation of cancer researchers by providing new and early career investigators
opportunities to successfully pursue high-impact research for the prevention, detection, and
treatment of cancer.

LINK to RFA

In-vivo Methods for Assessing Placental Development and Function (R41/R42)

RFA-HD-14-004


Background
The placenta is essential for the maintenance of pregnancy. The prominent function of the placenta is in the transfer of nutrients, gases and waste products between the mother and fetus. It is effectively the lung, gut, and kidney of the fetus. Abnormalities of placental development and function are known to underlie many major pathologies of pregnancy including spontaneous preterm birth, fetal growth restriction, and preeclampsia. Most information on placental biology is obtained studying placental tissue obtained from pathological pregnancies, such as a preterm deliveries occurring predominately in the third trimester, or from term deliveries in which placental development has already crested.  Hence, there is a paucity of information obtained earlier in gestation, a period of time when many of the pregnancy pathologies are believed to have their origins, as well as limited information gleaned throughout gestation from normal pregnancies. The development of real-time, non-invasive (or minimally invasive) methods to assess the development and functionality of the placenta in vivo throughout gestation would serve as valuable research tools to enhance our understanding of placental biology and rooted pathologies. The development of these tools could lead to the identification of markers and predictors of pregnancy outcome, and provide a future foundation for better pregnancy monitoring in the clinical setting.
Scope/Work to be Performed
This FOA is for the development of safe, real-time, non-invasive (or minimally invasive), in vivo methods to assess the placenta to evaluate normal and abnormal development and function. These methods may include imaging or sensor technologies. The objective of this FOA is to push the field beyond existing paradigms, such as in vitro measurement of analytes obtained from maternal blood and/or Doppler velocimetry of the uterine arteries, both of which have been associated with placental function.  Applications for studies solely measuring biomarkers using in vitro methods of placental function will not be considered responsive. Similarly, studies focusing only on uterine artery Doppler waveforms as a measure of placental perfusion would not be considered responsive. Projects that would be responsive to this FOA include novel methods as well as adapting or optimizing current imaging or real-time analyte(s) sensing technologies. In the case of imaging technologies, the development of signaling markers, safe contrasting materials, and/or software enhancement will be deemed responsive. In regard to analyte sensors, multiplexing analyte measurements is preferable. Special consideration will be given to applications that develop methods that are applicable throughout pregnancy, preferably starting in early gestation during the period of trophoblast invasion and remodeling of the uterine spiral arteries, and which also establish reference values. Other areas of interest include, but are not limited to:
  • Development of in vivo methods to assess in vivo placental function.
  • Development of in vivo methods to assess in vivo placental metabolism.
  • Development of in vivo methods to measure placental nutrient transfer.
  • Development of in vivo methods to measure in vivo placental microvascular blood flow.
  • Development of in vivo methods to measure placental structural development.
  • Development of in vivo methods for the measurement of placental perfusion.
  • Development of in vivo methods for the measurement of placental function in complicated pregnancies and patterns of progression to disease states.
  • Development of in vivo methods for the spatial and temporal regional mapping of placental function and association with placental histopathology in normal and pathologic states.
  • Development of in vivo methods for the measurement of placental response to environmental stressors (e.g. oxygen levels, tobacco exposure, maternal exercise, psychological stress).
Human studies are preferable, but animal studies are acceptable to evaluate proof of concept and the safety of methods that are directly applicable for future translational studies in the human.

Key Dates
Posted Date
May 22, 2013
Open Date (Earliest Submission Date)
July 21, 2013
Letter of Intent Due Date(s)
July 21, 2013
Application Due Date(s)
August 21, 2013, by 5:00 PM local time of applicant organization.