Funding Opportunity – Biomedical Research: HIV Persistence and Eradication

Request for Proposals: Targeted Biomedical Research

Exploring the mechanisms for HIV persistence and the potential for HIV eradication.

Please click here to access the full RFP: http://www.amfar.org/In_the_Lab/Research_Grants/

DEADLINE:
September 27, 2012, 5:00 PM (EDT)

AVAILABLE FUNDING AND PERFORMANCE PERIODMaximum total costs: $180,000 including indirect costs at a maximum of 20% of direct costs for a one year performance period starting February 1, 2013.

QUALIFICATIONSInvestigators must hold a doctoral degree and be affiliated with a nonprofit research institution.

LOI FOMS AND INSTRUCTIONSEligible applicants should request LOI forms and instructions by sending an e-mail to grants@amfar.org. E-mails should include (1) investigator’s name, doctoral degree(s), and job title(s), (2) name of the applicant institution, and (3) proposed project title.

BACKGROUNDThis RFP solicits proposals relevant to exploring the mechanisms for HIV persistence and the potential for HIV eradication. Highly active antiretroviral therapy (HAART) has significantly impacted the health of individuals infected with HIV-1. However, if therapy is interrupted, there is a rapid resumption of viral replication. Understanding the mechanisms by which the virus is able to persist in the face of therapy is necessary in order to identify strategies that may interrupt viral persistence and ultimately lead to viral eradication. amfAR wishes to support basic, pre-clinical, clinical, and especially translational research exploring the mechanisms whereby HIV infection persists; the chronic nature of viral reservoirs and latency; and barriers to the eradication of HIV, with the potential goal of ultimately eliminating HIV infection.

See the RFP posted at http://www.amfar.org/In_the_Lab/Research_Grants/ for details about specific areas of interest, submission requirements and additional information.