PROGRAM GOAL
The Michael J. Fox Foundation for Parkinson’s Research (MJFF) seeks to fund pre-clinical studies that investigate the biological function and therapeutic potential of Parkin protein. The ultimate goal is to identify therapeutic agents that alter the course of Parkinson’s disease.
There will be two separate ‘Tracks’ that may be pursued for support around Parkin as follows:
- TRACK A – Biology
- TRACK B – Therapeutic Development
Applicants may submit proposals to both Track A and Track B but it will need to do so by submitting separate applications that provide independent experimental designs for each. Applicants will be asked to justify the approach and to provide details of their study design.
Biological Studies
- How will the proposed studies impact our understanding of Parkin:
- As an enzyme
- In cell biology
Therapeutic Development Studies
- Current drug development stage with clear justification
- Provide research operation plan, including feasibility, timelines, and all assays to be performed
- Provide a clear description of the properties of the lead compound(s)/biologic
DEADLINES
- Informational Conference Call*: June 6, 2013, 12:00 p.m. EST
- Pre-proposals Due: June 19, 2013, 6:00 p.m. EST
- Full Application Invites Sent to Applicants: July 3, 2013
- Full Applications Due (by invite only): August 14, 2013
- Anticipated Award Announcement: October, 2013
- Anticipated Funding: November, 2013
*MJFF will hold a 45-minute conference call at the time listed above to clarify and explain the goals of this funding initiative and answer applicant questions.
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