Fox Foundation for Parkinson's Research, Michael J. (MJFF)

PROGRAM GOAL The Michael J. Fox Foundation for Parkinson’s Research (MJFF) seeks to stimulate development of Parkinson’s disease (PD) therapeutics with potential for fundamentally altering disease course and/or significantly improving treatment of symptoms above and beyond current standards of care. Part of our annual Edmond J. Safra Core Programs for PD Research, the Therapeutic Pipeline Program is open to industry and academic investigators working at either pre-clinical or clinical stages of drug and therapeutic development. Proposals must focus on a treatment strategy with clear potential for PD and have a well-defined plan for moving toward clinical utility for patients. Both novel approaches as well as repositioning of approved or clinically safe therapies from other non-PD indications are of interest. Applicant will be asked to justify the therapeutic targets relevant for PD, provide details of the therapeutic strategy, and clearly identify any suboptimal properties of their therapeutic strategy. Considerations include: The target and pathway proposed: What is the relevance of the proposed target for PD? What is the relationship of the proposed target within the pathway in which it is implicated to other potential targets? Why is the proposed target the most relevant in that pathway – in comparison to other targets in the same pathway? The therapeutic strategy: Current drug development stage with clear justification Provide research operation plan, including feasibility, timelines, and all assays to be performed Provide a clear description (strengths and weaknesses) of the properties of the proposed therapeutic DEADLINES Spring 2014 Review Cycle Informational Conference Call*: September 18, 2013 at 12pm US ET Pre-Proposals Due: October 30, 2013 – 6pm US ET Full Proposal Invitations: November 20, 2013 Full Proposals Due (by invite only): January 15, 2014– 6pm US ET Anticipated Award Announcement: March 2014 Anticipated Funding: April 2014 https://www.michaeljfox.org/research/grant-detail.php?id=9