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Wednesday, August 28, 2013

Department of Defense (DoD) Breast Cancer Research Program (BCRP) Breakthrough Award


Funding Opportunity Number: W81XWH-13-BCRP-BREAKTHROUGH2
Catalog of Federal Domestic Assistance Number: 12.420
 Pre-Application Submission Deadline: 5:00 p.m. Eastern time (ET), October 8, 2013
 Invitation to Submit an Application: November 2013
 Application Submission Deadline: 11:59 p.m. ET, January 15, 2014
 Peer Review: March 2014
 Programmatic Review: May 2014

FY13 BCRP Overarching Challenges
Considering the current breast cancer landscape and the BCRP’s vision to end breast cancer,
each FY13 BCRP Breakthrough Award application must address at least one of the following
Overarching Challenges:
 Eliminate the mortality associated with metastatic breast cancer
 Prevent breast cancer (primary prevention)
 Distinguish aggressive breast cancer from indolent cancers; overcome the problems of
overdiagnosis and overtreatment
 Revolutionize treatment regimens by replacing drugs that have life-threatening
toxicities with safe, effective interventions
 Identify what drives breast cancer growth and metastasis; identify why some breast
cancers become life-threatening metastases
 Identify what makes the breast susceptible to cancer development
 Determine why some, but not all, women get breast cancer
 Determine why/how breast cancer cells lay dormant for years and then re-emerge
(recurrence); determine how to eliminate dormant cells earlyDoD FY13 Breast Cancer Breakthrough2 Award 4
Alternatively, with adequate justification, applications may identify and address another
Overarching Challenge related to the breast cancer landscape. Justification must be provided in
the pre-application.
C. Award Inf

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