http://cdmrp.army.mil/funding/pa/13bcrpbreakthrough2_pa.pdf
Funding Opportunity Number: W81XWH-13-BCRP-BREAKTHROUGH2
Catalog of Federal Domestic Assistance Number: 12.420
SUBMISSION AND REVIEW DATES AND TIMES
Pre-Application Submission Deadline: 5:00 p.m. Eastern time (ET), October 8, 2013
Invitation to Submit an Application: November 2013
Application Submission Deadline: 11:59 p.m. ET, January 15, 2014
Peer Review: March 2014
Programmatic Review: May 2014
FY13 BCRP Overarching Challenges
Considering the current breast cancer landscape and the BCRP’s vision to end breast cancer,
each FY13 BCRP Breakthrough Award application must address at least one of the following
Overarching Challenges:
Eliminate the mortality associated with metastatic breast cancer
Prevent breast cancer (primary prevention)
Distinguish aggressive breast cancer from indolent cancers; overcome the problems of
overdiagnosis and overtreatment
Revolutionize treatment regimens by replacing drugs that have life-threatening
toxicities with safe, effective interventions
Identify what drives breast cancer growth and metastasis; identify why some breast
cancers become life-threatening metastases
Identify what makes the breast susceptible to cancer development
Determine why some, but not all, women get breast cancer
Determine why/how breast cancer cells lay dormant for years and then re-emerge
(recurrence); determine how to eliminate dormant cells earlyDoD FY13 Breast Cancer Breakthrough2 Award 4
Alternatively, with adequate justification, applications may identify and address another
Overarching Challenge related to the breast cancer landscape. Justification must be provided in
the pre-application.
C. Award Inf
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